News & Press Releases
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4/1/2015 - Ensemble is pleased to announce the publication of a paper in the Journal of Medicinal Chemistry that describes the use of DPC macrocyclic libraries in the discovery of novel XIAP antagonists. These macrocycles are potent pro-apoptotic agents, and are effective in shrinking tumors in a mouse xenograft model
1/1/2015 - Ensemble SAB member, Dr Simon Campbell, receives a knighthood for services to chemistry.
Ensemble Therapeutics is proud and delighted to congratulate their SAB member, Dr Simon Campbell CBE FRS, on being knighted in the United Kingdom 2015 New Year Honours List.
Sir Simon’s award reflects his significant contribution to drug discovery, as the leading member of the research teams that discovered Cardura, Norvasc and Viagra - drugs that have benefited millions of people worldwide.
During his tenure as President of The Royal Society of Chemistry he campaigned for more funding and an improved image for chemistry. Under his leadership, the Campaign for Chemistry reinvigorated chemistry education in the UK while the Simon and Jill Campbell Foundation supports state school students reading science and mathematics at Cambridge and Birmingham Universities. He was also the first chair of the Medicines for Malaria Venture, a landmark public-private partnership.
We look forward to Sir Simon’s continuing role as a scientific advisor to Ensemble, especially with respect to the company’s internal programs to develop novel macrocycle drugs against difficult-to-drug cancer targets.
8/6/2013 - Ensemble Therapeutics Forms Global Strategic Collaboration for Development of Oral, Macrocyclic IL-17 Antagonists and Additional Disease Targets.
7/18/2013 - Ensemble Therapeutics and Alexion Initiate Collaboration to Discover Macrocycle Drug Candidates Targeting Patients with Severe and Ultra-Rare Disorders
4/1/2013 - Ensemble Therapeutics to Present Data on IL-17A Inhibitors that are Novel, Oral Macrocycles Against Previously Undruggable Target
2/13/2013 - Ensemble Therapeutics Presents Data Demonstrating Unique Properties of Synthetic Macrocycles for Pursuing Challenging Targets
11/12/2012 - Ensemble Therapeutics Presents Oral Efficacy of First-in-Class Small Molecule Targeting IL-17 for Inflammation in Preclinical Studies
Download IL-17 ACR Poster
11/1/2012 - Ensemble Therapeutics and Boehringer Ingelheim Initiate Collaboration to Discover Macrocycle Drug Candidates
10/29/2012 - Ensemble Therapeutics to Present at 2012 ACR Annual Meeting
5/29/2012 - Ensemble Therapeutics and Genentech Initiate Collaboration to Discover Macrocyclic Drug Candidates
1/5/2012 - Ensemble Therapeutics Advances Macrocycle IL-17 Antagonist Program: Reports First Known Small Molecule Inhibitors of Important Autoimmune Target
1/5/2012 - Ensemble Therapeutics Extends Macrocycle Drug Discovery Alliance with Bristol-Myers Squibb
7/6/2011 - Ensemble Therapeutics Receives Two Notices of Allowance for Fundamental Patents to DNA-Programmed Chemistry for Novel Macrocycle Therapeutics
4/12/2011 - Ensemble Achieves Milestone in Bristol-Myers Squibb Collaboration
11/2/2010 - Ensemble Awarded Three Therapeutic Discovery Project Grants Totaling $744,000
9/15/2010 - Ensemble Therapeutics Appoints Ted Hibben as Senior Vice President, Corporate Development
8/23/2010 - Ensemble Therapeutics Presents Data at American Chemical Society National Meeting
6/22/2010 - Ensemble Evolves Name to Ensemble Therapeutics Corporation and Also Announces New Strategic Investor: Kisco Ltd.
1/6/2010 - Ensemble Discovery Initiates Collaboration with Pfizer to Develop Novel Drugs Against Protein-Protein Interaction Targets
4/15/2009 - Ensemble Discovery Initiates Collaboration with Bristol-Myers Squibb to Develop Drugs in Novel Therapeutic Class